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Boc-NH-PEG8-CH2CH2COOH

Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[1334169-93-5]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-nh-peg8-ch2ch2cooh.html

Purity

99.94

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Molecular Formula

C24H47NO12

Molecular Weight

541.63

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

Available Sizes

Curated Selection

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