AJS1669 (free acid)
AJS1669 free acid is a potent and orally available glycogen synthase (GS) activator. AJS1669 improves glucose metabolism and reduces body fat mass in mice[1].
Product Specifications
CAS Number
[1853130-05-8]
UNSPSC
12352005
Target
Glycosyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ajs1669-free-acid.html
Concentration
10mM
Purity
99.15
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)CN(C(C1=CC=C(COC2=CC=C(C3=CC(F)=C(F)C=C3SC)C=C2)O1)=O)CC4=CC=CO4
Molecular Formula
C26H21F2NO6S
Molecular Weight
513.51
References & Citations
[1]Nakano K, et al. AJS1669, a novel small-molecule muscle glycogen synthase activator, improves glucose metabolism and reduces body fat mass in mice. Int J Mol Med. 2017 Apr;39 (4) :841-850.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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