Isorhamnetin-3-O-neohespeidoside

Isorhamnetin-3-O-neohespeidoside is a flavonoid. Isorhamnetin-3-O-neohespeidoside can be isolated from Typha angustifolia. Isorhamnetin-3-O-neohespeidoside inhibits xanthine oxidase activity with an IC50 of 48.75 μg mL. Isorhamnetin-3-O-neohespeidoside has antioxidant and osteoclastogenic activities. Isorhamnetin-3-O-neohespeidoside can be used in research of bone[1][2][3].

Product Specifications

CAS Number

[55033-90-4]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Xanthine Oxidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/isorhamnetin-3-o-neohespeidoside.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C1C(O[C@H](O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H]2O[C@@](O[C@@H](C)[C@H](O)[C@H]3O)([H])[C@@H]3O)=C(C4=CC(OC)=C(O)C=C4)OC5=CC(O)=CC(O)=C15

Molecular Formula

C28H32O16

Molecular Weight

624.54

Precautions

H315, H319, H335

References & Citations

[1]Wang X, et al. A rapid and efficient extraction method based on industrial MCM-41-miniaturized matrix solid-phase dispersion extraction with response surface methodology for simultaneous quantification of six flavonoids in Pollen typhae by ultra-high-performance liquid chromatography. J Sep Sci. 2019 Jul;42 (14) :2426-2434.|[2]Bouhlel I, et al. Assessment of isorhamnetin 3-O-neohesperidoside from Acacia salicina: protective effects toward oxidation damage and genotoxicity induced by aflatoxin B1 and nifuroxazide. J Appl Toxicol. 2010 Aug;30 (6) :551-8. |[3]Yu X, et al. Isorhamnetin 3-O-neohesperidoside promotes the resorption of crown-covered bone during tooth eruption by osteoclastogenesis. Sci Rep. 2020 Mar 20;10 (1) :5172.