CCT007093
CCT007093 is an effective protein phosphatase 1D (PPM1D Wip1) inhibitor. Wip1 inhibition can activate the mTORC1 pathway and enhance hepatocyte proliferation after hepatectomy[1][2].
Product Specifications
CAS Number
176957-55-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Phosphatase
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CCT007093.html
Purity
98.34
Solubility
DMF : 3.33 mg/mL (ultrasonic) |DMSO : ≥ 2.8 mg/mL
Smiles
O=C1/C(CC/C1=C\C2=CC=CS2)=C/C3=CC=CS3
Molecular Formula
C15H12OS2
Molecular Weight
272.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Lingling Zhang, et al. Inhibition of wild-type p53-induced phosphatase 1 promotes liver regeneration in mice by direct activation of mammalian target of rapamycin. Hepatology. 2015 Jun;61 (6) :2030-41.|[2]S Rayter, et al. A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. Oncogene. 2008 Feb 14;27 (8) :1036-44.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K7549808 1.0 µg DNA
Gabbr2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
Sign In for Pricing
View Details 
K3136304 1.0 µg DNA
9530053A07Rik sgRNA CRISPR Lentivector (Mouse) (Target 3)
Sign In for Pricing
View Details