VEGFR-2-IN-56
VEGFR-2-IN-56 (compund 12e) is a potent VEGFR-2 inhibitor (IC50=45.9 nM) [1].
Product Specifications
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-56.html
Smiles
O=C(N1CCC(C(N/N=C2C(NC3=C\2C=C(Br)C=C3)=O)=O)CC1)NC4=CC=C(OC)C=C4
Molecular Formula
C22H22BrN5O4
Molecular Weight
500.35
References & Citations
[1]Eldehna WM, et al. Design, synthesis, and in silico insights of novel N'- (2-oxoindolin-3-ylidene) piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors. Bioorg Chem. 2024 Dec;153:107829.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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