UPCDC30766
Product Specifications
UNSPSC Description
UPCDC30766 is a potent allosteric inhibitor of p97, with an IC50 of 12 nM. UPCDC30766 can be used for the research of colon cancer[1]. UPCDC30766 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
p97
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/upcdc30766.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC#CC1=C(F)C=C(OCC2=NN=C(S[C@H]3C=CCCC3)N2C4=CC=CN=C4)C(F)=C1)NC5CCN(C)CC5
Molecular Weight
594.68
References & Citations
[1]LaPorte MG, et, al. Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer. ACS Med. Chem. Lett. 2023, 14, 7, 977-985.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155026/UPCDC30766-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155026/UPCDC30766-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2152623-68-0
Available Sizes
Curated Selection
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