UPCDC30766
UPCDC30766 is a potent allosteric inhibitor of p97 (IC50 of 12 nM; EC50 of 0.23 μM in cells) . UPCDC30766 can be used for the research of colon cancer[1].
Product Specifications
CAS Number
[2152623-68-0]
UNSPSC
12352005
Target
P97
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/upcdc30766.html
Purity
99.33
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OCC#CC1=C(F)C=C(OCC2=NN=C(S[C@H]3C=CCCC3)N2C4=CC=CN=C4)C(F)=C1)NC5CCN(C)CC5
Molecular Formula
C30H32F2N6O3S
Molecular Weight
594.68
References & Citations
[1]LaPorte MG, et, al. Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer. ACS Med. Chem. Lett. 2023, 14, 7, 977-985.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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