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UPCDC30766

UPCDC30766 is a potent allosteric inhibitor of p97 (IC50 of 12 nM; EC50 of 0.23 μM in cells) . UPCDC30766 can be used for the research of colon cancer[1].

Product Specifications

CAS Number

2152623-68-0

UNSPSC

12352005

Target

P97

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/upcdc30766.html

Purity

99.33

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OCC#CC1=C(F)C=C(OCC2=NN=C(S[C@H]3C=CCCC3)N2C4=CC=CN=C4)C(F)=C1)NC5CCN(C)CC5

Molecular Formula

C30H32F2N6O3S

Molecular Weight

594.68

References & Citations

[1]LaPorte MG, et, al. Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer. ACS Med. Chem. Lett. 2023, 14, 7, 977-985.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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