What is the catalog number for ATP?

The catalog number for ATP is HY-B2176.

What sizes are available for ATP?

ATP is available in the following size(s): 100 mg, 500 mg, 1 g, 5 g, 10 g.

How many pack sizes does ATP come in?

ATP is available in 5 different pack sizes.

ATP is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ATP?

ATP is manufactured by QuantiMol.

What is the estimated delivery time for ATP?

Estimated delivery time for ATP is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ATP?

The safety data sheet for ATP is available here: http://file.medchemexpress.com/batch_PDF/HY-B2176/ATP-SDS-MedChemExpress.pdf.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

ATP

ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice[1][2][3][4].

Product Specifications

CAS Number

56-65-5

Product Name Alternative

Adenosine 5'-triphosphate

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Endogenous Metabolite; Interleukin Related; NOD-like Receptor (NLR)

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ATP.html

Purity

99.88

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O

Molecular Formula

C10H16N5O13P3

Molecular Weight

507.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35 (3) :852-8.|[2]M J L Bours, et al. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112 (2) :358-404.|[3]Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov;107:104514.|[4]Yang Xiang, et al. Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013; 8 (5) : e63759.