Apiole (Standard)

Apiole (Standard) is the analytical standard of Apiole. This product is intended for research and analytical applications. Apiole is an anti-tumor agent that induces apoptosis and inhibits human colon cancer cells by inducing G0/G1 cell cycle arrest. Apiole also significantly inhibited colon tumor development in an in vivo mouse xenograft model[1][2].

Product Specifications

CAS Number

[523-80-8]

UNSPSC

12352005

Target

Apoptosis; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/apiole-standard.html

Smiles

C=CCC1=CC(OC)=C(OCO2)C2=C1OC

Molecular Formula

C12H14O4

Molecular Weight

222.24

References & Citations

[1]Wu KH, et al. Study of the antitumor mechanisms of apiole derivatives (AP-02) from Petroselinum crispum through induction of G0/G1 phase cell cycle arrest in human COLO 205 cancer cells. BMC Complement Altern Med. 2019 Jul 27;19 (1) :188.|[2]Wei PL, et al. The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5- (2-propen-1-yl) -1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate. J Cancer Res Ther. 2012 Oct-Dec;8 (4) :532-6.