Anti-Hemoglobin (Human) Mouse Monoclonal Antibody - Library Pack

Selection of Mouse Monoclonal antibodies specific to Hemoglobin (Human)

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Anti-Hemoglobin (Human) Mouse Monoclonal Antibody Library Pack - Includes 100 ug of each of the following antibodies: 19001 - Anti-Hemoglobin (Human) Mouse Monoclonal Antibody - Clone HB11-201.11 - Isotype IgG1 19002 - Anti-Hemoglobin (Human) Mouse Monoclonal Antibody - Clone HB11-203.1 - Isotype IgG1 19003 - Anti-Hemoglobin (Human) Mouse Monoclonal Antibody - Clone HB11-231.2 - Isotype IgG1

Host

Mouse

Reactivity

Human

Immunogen

Purified human hemoglobin.

Target

Hemoglobin (Human)

Clonality

Monoclonal

Type

Antibody Library Pack

Applications

WB, ELISA

Field of Research

Hormones/Proteins

Purification Method

Purified by Protein G affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Additionnal Information

These antibodies have been qualified for use in ELISA to detect human hemoglobin.

Storage Conditions

These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Specificity

These antibodies recognize human hemoglobin. They do not cross-react with hemoglobin of the following species: bovine, chicken, equine, ovine, or porcine.

Formulation

PBS, pH 7.4.

Buffer pH

pH 7.4

Target Background

Hemoglobin is the iron-containing oxygen-transport metalloprotein in red blood cells of all vertebrates as well as in the tissues of some invertebrates. In mammals, hemoglobin makes up about 35% of the total content of red blood cells. It has an oxygen-binding capacity of 1.34 mL O2 per gram, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood. The mammalian hemoglobin molecule can bind up to four oxygen molecules. Hemoglobin also carries some of the body's respiratory carbon dioxide (about 20â€“25% of the total) as carbaminohemoglobin as well as nitric oxide bound to a thiol group, releasing it at the same time as oxygen. Other cells that contain hemoglobin include the A9 dopaminergic neurons in the substantia nigra, macrophages, alveolar cells, and mesangial cells in the kidney. In these tissues, hemoglobin has a non-oxygen-carrying function as an antioxidant and a regulator of iron metabolism.