Dapivirine-d11
Dapivirine-d11 is the deuterium labeled Dapivirine. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI) . Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations[1][2].
Product Specifications
CAS Number
1329613-10-6
Product Name Alternative
TMC120-d11; R147681-d11
UNSPSC
12352005
Target
Apoptosis; Autophagy; HIV; Isotope-Labeled Compounds; Reverse Transcriptase
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Autophagy; Others
Field of Research
Infection
Purity
0.9967
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(NC2=NC=CC(NC3=C(C([2H])([2H])[2H])C([2H])=C(C([2H])([2H])[2H])C([2H])=C3C([2H])([2H])[2H])=N2)C=C1
Molecular Formula
C20H8D11N5
Molecular Weight
340.47
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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