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Propargyl-PEG1-NH2

Propargyl-PEG1-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG1-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

122116-12-5

Product Name Alternative

AZD0865

UNSPSC

12352211

Hazard Statement

H226, H314

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/propargyl-peg1-nh2.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C#CCOCCN

Molecular Formula

C5H9NO

Molecular Weight

99.13

Precautions

H226, H314

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Frequently Asked Questions

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