Ac32Az19
Ac32Az19 is a potent, nontoxic, and highly selective BCRP inhibitor with an EC50 value of 13 nM in the BCRP-overexpressed HEK293/R2 cells.
Product Specifications
CAS Number
[2760674-72-2]
UNSPSC
12352005
Target
BCRP
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac32az19.html
Purity
98.12
Solubility
DMSO : 60 mg/mL (ultrasonic)
Smiles
O=C1C(OCC2=CC(C(OC)=O)=CC=C2)=C(OC3=CC=CC=C31)C4=CC=C(C=C4)OCCCCC5=CN(N=N5)CC6=CC=CC=C6
Molecular Formula
C37H33N3O6
Molecular Weight
615.67
References & Citations
[1]Wong ILK, et al. Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2) . J Med Chem. 2021 Oct 14;64 (19) :14311-14331.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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