Ac32Az19

Ac32Az19 is a potent, nontoxic, and highly selective BCRP inhibitor with an EC50 value of 13 nM in the BCRP-overexpressed HEK293/R2 cells.

Product Specifications

CAS Number

[2760674-72-2]

UNSPSC

12352005

Target

BCRP

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ac32az19.html

Purity

98.12

Solubility

DMSO : 60 mg/mL (ultrasonic)

Smiles

O=C1C(OCC2=CC(C(OC)=O)=CC=C2)=C(OC3=CC=CC=C31)C4=CC=C(C=C4)OCCCCC5=CN(N=N5)CC6=CC=CC=C6

Molecular Formula

C37H33N3O6

Molecular Weight

615.67

References & Citations

[1]Wong ILK, et al. Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2) . J Med Chem. 2021 Oct 14;64 (19) :14311-14331.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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