Anti-Mouse CD71/TfR1 Antibody (8D3)
Anti-Mouse CD71/TfR1 Antibody (8D3) is a rat-derived anti-mouse CD71/TfR1 IgG2a type antibody inhibitor. Anti-Mouse CD71/TfR1 Antibody (8D3) depletes of CD71+ erythroid cells but does not change percentages of Tregs in neonatal mice. Anti-Mouse CD71/TfR1 Antibody (8D3) enhances neonatal mice defence against infection[1][2].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
Transferrin Receptor
Type
Inhibitory Antibodies
Related Pathways
Apoptosis
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/anti-mouse-cd71-tfr1-antibody-8d3.html
Purity
95.00
Solubility
10 mM in DMSO
Smiles
[Anti-MouseCD71/TfR1Antibody(8D3)]
Molecular Weight
(150 kDa)
References & Citations
[1]Goulet DR, Atkins WM. Considerations for the Design of Antibody-Based Therapeutics. J Pharm Sci. 2020 Jan;109 (1) :74-103.|[2]Elahi S, et al. Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection. Nature. 2013 Dec 5;504 (7478) :158-62.|[3]Shahbaz S, et al. CD71+VISTA+ erythroid cells promote the development and function of regulatory T cells through TGF-β. PLoS Biol. 2018 Dec 14;16 (12) :e2006649.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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