Implitapide
Product Specifications
UNSPSC Description
Implitapide (AEGR 427) is a microsomal triglyceride transfer protein (MTP) inhibitor.
Target Antigen
Microsomal Triglyceride Transfer Protein (MTP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Implitapide.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(C2=C3C=CC=C2)C(N3CC4=CC=C([C@H](C5CCCC5)C(N[C@H](C6=CC=CC=C6)CO)=O)C=C4)=NC(C)=C1
Molecular Weight
531.69
References & Citations
[1]Ueshima K, et al. Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: involvement of the inhibition of postprandial triglyceride elevation. Biol Pharm Bull. 2005 Feb;28(2):247-52.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106130/Implitapide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106130/Implitapide-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
177469-96-4
Available Sizes
Curated Selection
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