Human FGF16 Protein

FGF16 is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the MEF2 site resulted in a blunting of FGF16 promoter activity in transfected neonatal rat cardiac myocytes, that chromatin remodeling and MEF2 binding in the FGF16 promoter contribute to expression in the postnatal heart.

Product Specifications

Background

Product Name Alternative

FGF16; Fibroblast Growth Factor 16; Metacarpal 4-5 Fusion; FGF-16; MF4

Gene ID

8823

Accession Number

O43320

Tag

FGF16

Type

Cytokines and proteins

Applications

No tag

Purity

> 98 % as determined by SDS-PAGE

Activity

Measured by its ability to induce proliferation in Balb/3T3 cells. The ED50 for this effect is 5.997 ng/mL.

Molecular Weight

23.6 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA , 10%FBS or 0.1%BSA) . Please prevent freeze-thaw cycles

Protein Length

The recombinant Human FGF16 consists of 206 amino acids and predicts a molecular mass of 23.6 kDa.

Formulation

Lyophilized from 20 mM Tris-HCl, 500 mM NaCl, pH8.0

Applications Notes

Human

Other Product Names

FGF16; Fibroblast Growth Factor 16; Metacarpal 4-5 Fusion; FGF-16; MF4

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously.