Xanthoxylin

Xanthoxylin (Xanthoxyline) can be isolated from Zanthoxylum simulans. Xanthoxylin has antifungal and antioxidant effects. The MIC of Xanthoxylin against Toxoplasma neonatorum and Aspergillus fumigatus were 50 µg/mL and 75 µg/mL, respectively. Xanthoxylin can be used in the study of anti-epileptic diseases[1][2][3].

Product Specifications

CAS Number

[90-24-4]

Product Name Alternative

Xanthoxyline

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/xanthoxylin.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=C(OC)C=C(OC)C=C1O)=O

Molecular Formula

C10H12O4

Molecular Weight

196.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Cechinel Filho V, et al. Antispasmodic activity of xanthoxyline derivatives: structure-activity relationships.J Pharm Sci. 1995 Apr;84 (4) :473-5.|[2]Pinheiro TR, et al. In vitro antifungal evaluation and studies on the mode of action of xanthoxyline derivatives.Arzneimittelforschung. 1999 Dec;49 (12) :1039-43.|[3]Moleephan W, et al. Effect of xanthoxylin on melanin content and melanogenic protein expression in B16F10 melanoma. Asian Biomedicine, 2012, 6 (3) : 413-422.