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Clavulanic acid

Product Specifications

UNSPSC Description

Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias[1].

Target Antigen

Antibiotic; Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/clavulanic-acid.html

Purity

99.76

Solubility

DMSO : 13.89 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 7 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O

Molecular Weight

199.162

References & Citations

[1]Parag S Saudagar, et al. Clavulanic acid: a review. Biotechnol Adv. Jul-Aug 2008;26(4):335-51|[2]Neu HC, et al. Clavulanic acid, a novel inhibitor of beta-lactamases. Antimicrob Agents Chemother. 1978 Nov;14(5):650-5.|[3]Beceiro A,et al. In vitro activity and in vivo efficacy of clavulanic acid against Acinetobacter baumannii. Antimicrob Agents Chemother. 2009 Oct;53(10):4298-304.|[4]Soyocak A, et al. Tannic acid exhibits anti-inflammatory effects on formalin-induced paw edema model of inflammation in rats. Hum Exp Toxicol. 2019 Nov;38(11):1296-1301.Eur J Pharmacol. 2024 Sep 28:177017.|Genomics. 2022: 110527.|Int J Mol Sci. 2023 Oct 27, 24(21), 15657.|Biomed Res Int. 2018 Jul 2;2018:3579832. |bioRxiv. 2024 May 10.|Nat Commun. 2022 Mar 2;13(1):1116.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-A0256/Clavulanic-acid-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-A0256/Clavulanic-acid-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

58001-44-8

Available Sizes

Curated Selection

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