Phospho-Lck (Tyr505) Rabbit FITC Conjugate

<strong>Phospho-Lck (Tyr505) Rabbit FITC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018804_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Tyrosine-protein kinase Lck, Leukocyte C-terminal Src kinase, LSK, Protein YT16, T cell-specific protein-tyrosine kinase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Jullien P, Bougeret C, Camoin L, Bodeus M, Durand H, Disanto JP, Fischer S, Benarous R. Tyr394 and Tyr505 are autophosphorylated in recombinant Lck protein-tyrosine kinase expressed in Escherichia coli Eur J Biochem. 1994 Sep 1;224(2):589-96._x000D_ 2: Zhu J, Yan H, Shi M, Zhang M, Lu J, Wang J, Chen L, Wang Y, Li L, Miao L, Zhang H. Luteolin inhibits spike protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) binding to angiotensin-converting enzyme 2 Phytother Res. 2023 Aug;37(8):3508-3521._x000D_ 3: Shevelev I, Blanca G, Villani G, Ramadan K, Spadari S, Hübscher U, Maga G. Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities Nucleic Acids Res. 2003 Dec 1;31(23):6916-25._x000D_ 4: Payne G, Shoelson SE, Gish GD, Pawson T, Walsh CT. Kinetics of p56lck and p60src Src homology 2 domain binding to tyrosine-phosphorylated peptides determined by a competition assay or surface plasmon resonance Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4902-6._x000D_ 5: Liu MS, Tsai HY, Liu XX, Ho MC, Wu WJ, Tsai MD. Structural Mechanism for the Fidelity Modulation of DNA Polymerase λ J Am Chem Soc. 2016 Feb 24;138(7):2389-98._x000D_ 6: D'Oro U, Ashwell JD. Cutting edge: the CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes J Immunol. 1999 Feb 15;162(4):1879-83._x000D_ 7: Borowicz P, Sundvold V, Chan H, Abrahamsen G, Kjelstrup H, Nyman TA, Spurkland A. Tyr(192) Regulates Lymphocyte-Specific Tyrosine Kinase Activity in T Cells J Immunol. 2021 Aug 15;207(4):1128-1137._x000D_ 8: Foley MC, Schlick T. Relationship between conformational changes in pol lambda's active site upon binding incorrect nucleotides and mismatch incorporation rates J Phys Chem B. 2009 Oct 1;113(39):13035-47._x000D_ 9: Pryshchep S, Goronzy JJ, Parashar S, Weyand CM. Insufficient deactivation of the protein tyrosine kinase lck amplifies T-cell responsiveness in acute coronary syndrome Circ Res. 2010 Mar 5;106(4):769-78._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/10400611">10: Hartley DA, Hurley TR, Hardwick JS, Lund TC, Medveczky PG, Sefton BM. Activation of the lck tyrosine-protein kinase by the binding of the tip protein of herpesvirus saimiri in the absence of regulatory tyrosine phosphorylation J Biol Chem. 1999 Jul 16;274(29):20056-9. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Lck (Tyr505) Rabbit FITC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>