ST-1006
ST-1006 is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 has anti-inflammatory effect[1][2].
Product Specifications
CAS Number
1196994-11-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/st-1006.html
Purity
99.55
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
ClC(C=CC=C1Cl)=C1CNC2=CC(N3CCN(CC3)C)=NC(N)=N2
Molecular Formula
C16H20Cl2N6
Molecular Weight
367.28
Precautions
H302, H315, H319
References & Citations
[1]Adami M, et, al. Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice. Naunyn Schmiedebergs Arch Pharmacol. 2018 Dec;391 (12) :1387-1397.|[2]Mommert S, et, al. Human basophil chemotaxis and activation are regulated via the histamine H4 receptor. Allergy. 2016 Sep;71 (9) :1264-73.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H4 Receptor
Available Sizes
Frequently Asked Questions
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