Mouse IRAK4 Protein, His Tag (active enzyme)
Mouse IRAK4 Protein, His Tag (IR4-M5544) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ala 459 (Accession # Q8R4K2-1) .
Product Specifications
Background
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 52.9 kDa.
Accession Number
Q8R4K2-1
Expression Region
Met 1 - Ala 459
Host
Insect Cells
Target
IRAK4
Conjugation
Unconjugated
Tag
N-10xHis
Source
Mouse
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Format
Liquid
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Additives
Glycerol
Molecular Weight
52.9 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/IR4-M5544.pdf
Species
Mouse
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