Anti-Mouse myeloperoxidase/MPO Antibody (6D1)
Anti-Mouse myeloperoxidase/MPO Antibody (6D1) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to mouse Mouse myeloperoxidase/MPO. Anti-Mouse myeloperoxidase/MPO Antibody (6D1) can induce anti-neutrophil associated antibody (ANCA) mediated vasculitis in mice[1][2].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
Peroxidase Enzyme
Type
Inhibitory Antibodies
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-mouse-myeloperoxidase-mpo-antibody-6d1.html
Smiles
[Anti-Mousemyeloperoxidase/MPOAntibody(6D1)]
Molecular Weight
(150 kDa)
References & Citations
[1]Kessler N, et al. Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing. J Exp Med. 2022 Oct 3;219 (10) :e20220759.|[2]Fayçal CA, et al. An adapted passive model of anti-MPO dependent crescentic glomerulonephritis reveals matrix dysregulation and is amenable to modulation by CXCR4 inhibition. Matrix Biol. 2022 Feb;106:12-33.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Frequently Asked Questions
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