TAO Kinase inhibitor 2
TAO Kinase inhibitor 2 (Example 49) is a TAO Kinase inhibitor (IC50=between 50 and 500 nM) . TAO Kinase inhibitor 2 also inhibits KIAA1361 and JIK with IC50s of 50-500 nM[1].
Product Specifications
CAS Number
[850467-77-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tao-kinase-inhibitor-2.html
Purity
97.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CC=C(C=C1)OC2=CC=CC=C2)NCC(NC3C4=C(CCC3)C=CC=C4)=O
Molecular Formula
C25H24N2O3
Molecular Weight
400.47
Precautions
H302, H315, H319
References & Citations
[1]Deborah Lynn Baly, et al. Tao kinase modulators and methods of use. Patent. WO2005040355.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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