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N-Boc-dolaproine (dicyclohexylamine)

N-Boc-dolaproine dicyclohexylamine is an amino acid residue of the pentapeptide Dolastatin 10 (HY-15580) . Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity. And contains dicyclohexylamine[1].

Product Specifications

CAS Number

[1369427-40-6]

Product Name Alternative

(2R,3R) -BOC-dolaproine (dicyclohexylamine)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Microtubule/Tubulin; Mitosis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-boc-dolaproine-dicyclohexylamine.html

Purity

99.95

Solubility

Ethanol : 100 mg/mL (ultrasonic)

Smiles

CO[C@H]([C@@H](C)C(O)=O)[C@H]1N(C(OC(C)(C)C)=O)CCC1.C2(NC3CCCCC3)CCCCC2

Molecular Formula

C26H48N2O5

Molecular Weight

468.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44 (5) : 937-940.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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