Propiconazole

Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals[1][2].

Product Specifications

CAS Number

[60207-90-1]

UNSPSC

12352005

Hazard Statement

H302, H317, H360, H400, H410

Target

Fungal; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/propiconazole.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCC1OC(CN2N=CN=C2)(C3=CC=C(Cl)C=C3Cl)OC1

Molecular Formula

C15H17Cl2N3O2

Molecular Weight

342.22

Precautions

H302, H317, H360, H400, H410

References & Citations

[1]Guobin Sun, et al. Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver. Toxicol Lett. 2005 Feb 15;155 (2) :277-87.|[2]ShuangLi, et al. Single and Combined Cytotoxicity Research of Propiconazole and Nano-zinc Oxide on the NIH/3T3 Cell. Procedia Environmental Sciences Volume 18, 2013, Pages 100-105.