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STING agonist-1

Product Specifications

UNSPSC Description

STING agonist-1 (G10) is human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses. G10 potently blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM[1].

Target Antigen

STING; Virus Protease

Type

Reference compound

Related Pathways

Anti-infection;Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/STING-agonist-1.html

Purity

99.93

Solubility

DMSO : 75 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(SCC(N2CC3=C(F)C=CC=C3Cl)=O)C2=C1)NCC4=CC=CO4

Molecular Weight

430.88

References & Citations

[1]Sali TM, et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog. 2015 Dec 8;11(12):e1005324.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-19711/STING-agonist-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-19711/STING-agonist-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

702662-50-8

Available Sizes

Curated Selection

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