Fumitremorgin C
Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor.
Product Specifications
CAS Number
[118974-02-0]
Product Name Alternative
12α-Fumitremorgin C
UNSPSC
12352005
Target
Antibiotic; Bacterial; BCRP
Type
Natural Products
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Fumitremorgin_C.html
Purity
99.90
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@]1([H])CC2=C([C@H](/C=C(C)\C)N13)NC4=C2C=CC(OC)=C4)N5[C@](CCC5)([H])C3=O
Molecular Formula
C22H25N3O3
Molecular Weight
379.45
References & Citations
[1]Rabindran SK, et al. Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res. 1998 Dec 15;58 (24) :5850-8.|[2]Rabindran SK, et al. Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res. 2000 Jan 1;60 (1) :47-50.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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