ALX-5407 (hydrochloride)

ALX-5407 ((R) -NFPS) hydrochloride is a selective and orally active glycine transporter GlyT1 inhibitor with an IC50 value of 3 nM. ALX-5407 hydrochloride can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia[1].

Product Specifications

CAS Number

[200006-08-2]

Product Name Alternative

(R) -NFPS (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H410

Target

GlyT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/alx-5407-hydrochloride.html

Purity

98.36

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC1=CC=C([C@H](OC2=CC=C(C3=CC=CC=C3)C=C2)CCN(C)CC(O)=O)C=C1.[H]Cl

Molecular Formula

C24H25ClFNO3

Molecular Weight

429.91

Precautions

H302, H410

References & Citations

[1]Atkinson BN, et al. ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter. Mol Pharmacol. 2001 Dec;60 (6) :1414-20.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

sc-349912 250 mg

5- (1,1-dioxidotetrahydrothien-3-yl) -1,3,4-oxadiazole-2-thiol

Ask

View Details

MBS8427990-01 0.02 mg

Human STK38 Protein Lysate

Ask

View Details

MBS8427990-02 5x 0.02 mg

Human STK38 Protein Lysate

Ask

View Details

MR227570 10 µg

Hspa5 (NM_022310) Mouse Tagged ORF Clone

Ask

View Details

NBP2-98144IR 0.1 mL

Rabbit Polyclonal FBXO27 Antibody [DyLight 755]

Ask

View Details

RC214628L3V 200 µL

FRS2 (NM_001042555) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details