I-BRD9
I-BRD9 is a selective cellular chemical probe for bromodomain-containing protein 9 (BRD9) . I-BRD9 has a pIC50value of 7.3 for BRD9 inhibitor, with greater than 700-fold selectivity over the BET family and 200-fold over the highly homologous bromodomain-containing protein 7 (BRD7) . I-BRD9 is also shows a greater than 70-fold selectivity against a panel of 34 bromodomains. I-BRD9 downregulates CLEC1, DUSP6, FES and SAMSN1 genes in Kasumi-1 cells.
Product Specifications
CAS Number
1714146-59-4
Format
Solid
Molecular Formula
C22H22F3N3O3S2
Shipping Conditions
Room Temperature
Storage Conditions
At least 6 months at -20°C.
Calculated Molecular Weight
497.6 Da
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