AC-263093 (free base)
AC-263093 free base (AC-093) functionally activates NPFFR2 and blocks activation of NPFFR1 with pKis of 6.9 and 7.0, respectively. AC-263093 free base has the potential for reversing opiate tolerance research[1]. .
Product Specifications
CAS Number
[849459-86-5]
Product Name Alternative
AC-093
UNSPSC
12352005
Target
Neuropeptide FF Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ac-263093-free-base.html
Purity
99.81
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
BrC1=CC=C(/C=N/NC(N)=N)C=C1Br
Molecular Formula
C8H8Br2N4
Molecular Weight
319.98
References & Citations
[1]David H Malin, et al. Reversal of morphine tolerance by a compound with NPFF receptor subtype-selective actions. Neurosci Lett. 2015 Jan 1:584:141-5.|[2]David H Malin, et al. Reversal of morphine tolerance by a compound with NPFF receptor subtype-selective actions. Neurosci Lett. 2015 Jan 1:584:141-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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