PC5-VC-PAB-MMAE

PC5-VC-PAB-MMAE consists the ADCs linker (PC5-VC-PAB) and potent tubulin inhibitor (MMAE) . PC5-VC-PAB-MMAE is a agent-linker conjugate for ADC[1].

Product Specifications

CAS Number

[2922216-98-4]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; Microtubule/Tubulin

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pc5-vc-pab-mmae.html

Purity

99.76

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC(OC4=C(C(F)=C(C(F)=C4F)F)F)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O

Molecular Formula

C69H99F5N10O15

Molecular Weight

1403.57

References & Citations

[1]Zhaohui LI, et al. Anti-cd39 antibody-drug conjugate and use thereof. China, WO2023051712. 2023-04-06.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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