PC5-VC-PAB-MMAE
PC5-VC-PAB-MMAE consists the ADCs linker (PC5-VC-PAB) and potent tubulin inhibitor (MMAE) . PC5-VC-PAB-MMAE is a agent-linker conjugate for ADC[1].
Product Specifications
CAS Number
[2922216-98-4]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pc5-vc-pab-mmae.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC(OC4=C(C(F)=C(C(F)=C4F)F)F)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
Molecular Formula
C69H99F5N10O15
Molecular Weight
1403.57
References & Citations
[1]Zhaohui LI, et al. Anti-cd39 antibody-drug conjugate and use thereof. China, WO2023051712. 2023-04-06.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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