BPR1J-097 Hydrochloride

BPR1J-097 Hydrochloride is a novel and potent FLT3 inhibitor with an IC50 of 11 nM.

Product Specifications

UNSPSC

12352005

Target

FLT3

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BPR1J-097_Hydrochloride.html

Purity

99.20

Solubility

DMSO : 6 mg/mL (ultrasonic; warming) |H2O : 2 mg/mL (ultrasonic)

Smiles

O=C(NC1=NNC(C2=CC=CC(NS(=O)(C3=CC=CC=C3)=O)=C2)=C1)C4=CC=C(N5CCN(C)CC5)C=C4.Cl

Molecular Formula

C27H29ClN6O3S

Molecular Weight

553.08

References & Citations

[1]Lin WH, et al. BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML. Br J Cancer. 2012 Jan 31;106 (3) :475-81.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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