Virodhamine
Product Specifications
Product Name Alternative
MSC2363318A
UNSPSC Description
Virodhamine is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine induces megakaryocytic differentiation by triggering MAPK signaling and ROS production. Virodhamine can be used for the research of various neurological disorders such as Alzheimer's and Parkinson's diseases[1][2].
Target Antigen
Cannabinoid Receptor; Endogenous Metabolite
Type
Reference compound
Related Pathways
GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/virodhamine.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCCN)=O
Molecular Weight
347.53
References & Citations
[1]Sharma DS, et al. Virodhamine, an endocannabinoid, induces megakaryocyte differentiation by regulating MAPK activity and function of mitochondria. J Cell Physiol. 2021 Feb;236(2):1445-1453.|[2]Hayase T. Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. BMC Neurosci. 2013 Feb 9;14:20.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116418/Virodhamine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116418/Virodhamine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
287937-12-6
Available Sizes
Curated Selection
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