Virodhamine

Product Specifications

CAS Number

[287937-12-6]

Product Name Alternative

MSC2363318A

UNSPSC Description

Virodhamine is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine induces megakaryocytic differentiation by triggering MAPK signaling and ROS production. Virodhamine can be used for the research of various neurological disorders such as Alzheimer's and Parkinson's diseases[1][2].

Target Antigen

Cannabinoid Receptor; Endogenous Metabolite

Type

Reference compound

Related Pathways

GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/virodhamine.html

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCCN)=O

Molecular Weight

347.53

References & Citations

[1]Sharma DS, et al. Virodhamine, an endocannabinoid, induces megakaryocyte differentiation by regulating MAPK activity and function of mitochondria. J Cell Physiol. 2021 Feb;236(2):1445-1453.|[2]Hayase T. Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. BMC Neurosci. 2013 Feb 9;14:20.