Altretamine
Altretamine is an alkylating antineoplastic agent.
Product Specifications
CAS Number
645-05-6
Product Name Alternative
ENT-50852; RB-1515; WR-95704
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Altretamine.html
Purity
99.94
Solubility
DMSO : 8.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1
Molecular Formula
C9H18N6
Molecular Weight
210.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Kelner MJ, et al. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol. 2008 Dec;63 (1) :19-26.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
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