Altretamine

Altretamine is an alkylating antineoplastic agent.

Product Specifications

CAS Number

[645-05-6]

Product Name Alternative

ENT-50852; RB-1515; WR-95704

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA Alkylator/Crosslinker

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Altretamine.html

Purity

99.94

Solubility

DMSO : 8.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1

Molecular Formula

C9H18N6

Molecular Weight

210.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Kelner MJ, et al. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol. 2008 Dec;63 (1) :19-26.