Rolinsatamab talirine
Rolinsatamab talirine (ABBV 176) is an antibody-drug conjugate (ADC) targeting prolactin receptor (PRLR). Rolinsatamab talirine consists of rolinsatamab , an enzymatically cleavable peptide linker, and SGD-1882 (HY-101127).
Product Specifications
CAS Number
2095467-44-8
Product Name Alternative
ABBV 176
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rolinsatamab-talirine.html
Smiles
[Rolinsatamabtalirine]
References & Citations
[1]Mark G Anderson, et al. ABBV-176, a PRLR antibody drug conjugate with a potent DNA-damaging PBD cytotoxin and enhanced activity with PARP inhibition. BMC Cancer. 2021 Jun 9;21 (1) :681.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
Phase 1
Frequently Asked Questions
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