Butyryltimolol

Butyryltimolol, an effective precursor of Timolol, improves the corneal penetration of Timolol[1]. Butyryltimolol is a β-adrenergic blocker[2].

Product Specifications

CAS Number

[106351-79-5]

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/butyryltimolol.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCC(O[C@@H](CNC(C)(C)C)COC1=NSN=C1N2CCOCC2)=O

Molecular Formula

C17H30N4O4S

Molecular Weight

386.51

References & Citations

[1]Chang SC, et al. Relative effectiveness of prodrug and viscous solution approaches in maximizing the ratio of ocular to systemic absorption of topically applied timolol. Exp Eye Res. 1988 Jan;46 (1) :59-69.|[2]Potter DE, et al. Ocular and cardiac beta-antagonism by timolol prodrugs, timolol and levobunolol. Curr Eye Res. 1988 Aug;7 (8) :755-9.