Sapacitabine
Product Specifications
UNSPSC Description
Sapacitabine is an orally available nucleoside analog proagent that is structurally related to cytarabine.
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Sapacitabine.html
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C(N=C(NC(CCCCCCCCCCCCCCC)=O)C=C1)N1[C@H]2[C@@H](C#N)[C@H](O)[C@@H](CO)O2
Molecular Weight
490.64
References & Citations
[1]Serova M, et al. Antiproliferative effects of sapacitabine (CYC682), a novel 2'-deoxycytidine-derivative, in human cancer cells. Br J Cancer. 2007 Sep 3;97(5):628-36.|[2]Green SR, et al. Combination of sapacitabine and HDAC inhibitors stimulates cell death in AML and other tumour types. Br J Cancer. 2010 Oct 26;103(9):1391-9.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-16445/Sapacitabine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-16445/Sapacitabine-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
151823-14-2
Available Sizes
Curated Selection
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