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XMP-629

XMP-629 (XOMA-629), a cationic α-helical peptide, is a potent endotoxin inhibitor. XMP-629 exhibits broad-spectrum antimicrobial activity via an immunomodulatory mechanism. XOMA 629 has antimicrobial activity against Propionibacterium acnes, Staphylococcus aureus and Streptococcus pyogenesand[1][2].

Product Specifications

CAS Number

316805-65-9

Product Name Alternative

XOMA-629

UNSPSC

12352209

Target

Antibiotic; Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/xmp-629.html

Solubility

10 mM in DMSO

Smiles

NCCCC[C@@H](N)C(N[C@H](CC(C)C)C(N[C@H](CC1=CC=CC=C1)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C(N[C@H](CCC(N)=O)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@@H](C(O)=O)CC2=CC=CC3=C2C=CC=C3)=O)=O)=O)=O)CC4=CC=CC5=C4C=CC=C5)=O)=O)=O)=O

Molecular Formula

C67H93N15O11

Molecular Weight

1284.55

References & Citations

[1]Hancock RE, et, al. Modulating immunity as a therapy for bacterial infections. Nat Rev Microbiol. 2012 Mar 16;10 (4) :243-54.|[2]Bhopale GM. Antimicrobial Peptides: A Promising Avenue for Human Healthcare. Curr Pharm Biotechnol. 2020;21 (2) :90-96.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

Phase 2

Frequently Asked Questions

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