XMP-629
XMP-629 (XOMA-629), a cationic α-helical peptide, is a potent endotoxin inhibitor. XMP-629 exhibits broad-spectrum antimicrobial activity via an immunomodulatory mechanism. XOMA 629 has antimicrobial activity against Propionibacterium acnes, Staphylococcus aureus and Streptococcus pyogenesand[1][2].
Product Specifications
CAS Number
316805-65-9
Product Name Alternative
XOMA-629
UNSPSC
12352209
Target
Antibiotic; Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xmp-629.html
Solubility
10 mM in DMSO
Smiles
NCCCC[C@@H](N)C(N[C@H](CC(C)C)C(N[C@H](CC1=CC=CC=C1)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C(N[C@H](CCC(N)=O)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@@H](C(O)=O)CC2=CC=CC3=C2C=CC=C3)=O)=O)=O)=O)CC4=CC=CC5=C4C=CC=C5)=O)=O)=O)=O
Molecular Formula
C67H93N15O11
Molecular Weight
1284.55
References & Citations
[1]Hancock RE, et, al. Modulating immunity as a therapy for bacterial infections. Nat Rev Microbiol. 2012 Mar 16;10 (4) :243-54.|[2]Bhopale GM. Antimicrobial Peptides: A Promising Avenue for Human Healthcare. Curr Pharm Biotechnol. 2020;21 (2) :90-96.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 2
Frequently Asked Questions
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