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Phlotoxin-1

Phlotoxin-1 is a new member of the NaSpTx-1 family. Phlotoxin-1 has been purified originally from the venom of Phlogiellus sp., Theraphosidae Selenocosmiinae (endemic to Papua New Guinea) . Phlotoxin-1 inhibits Nav1.7 with an IC50 value of 39 ± 2 nM.

Product Specifications

Specifications

Blocker of Nav1.7 channel

Target

Na channels

Sequence

ACLGQWDSCDPKASKCCPNYACEWKYPWCRYKLF

Peptide Number

PHX001

Disulfide Bonds

Cys1-Cys4; Cys2-Cys5; Cys3-Cys6

N Terminal Sequence

H

C Terminal Sequence

OH

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