Hm1a
Hm1a has been identified from the venom of the spider Heteroscodra maculata. Hm1a has been described as a potent and selective agonist of the voltage-gated sodium channel Nav1.1 with an EC value of 38 nM. Nav1.1 is expressed in the CNS and mutations are associated with several disorders such as epilespy or autism.Smartox Biotechnology is pleased to offer a synthetic and functionally active Hm1a dedicated to research laboratory use only.
Product Specifications
Specifications
Selective agonist of Nav1.1
Target
Na channels
Sequence
ECRYLFGGCSSTSDCCKHLSCRSDWKYCAWDGTFS
Peptide Number
HMA001
Disulfide Bonds
Cys2-Cys16; Cys9-Cys21; Cys15-Cys28
N Terminal Sequence
H
C Terminal Sequence
OH
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