Phlotoxin-1
Phlotoxin-1 is a new member of the NaSpTx-1 family. Phlotoxin-1 has been purified originally from the venom of Phlogiellus sp., Theraphosidae Selenocosmiinae (endemic to Papua New Guinea) . Phlotoxin-1 inhibits Nav1.7 with an IC50 value of 39 ± 2 nM.
Product Specifications
Specifications
Blocker of Nav1.7 channel
Target
Na channels
Sequence
ACLGQWDSCDPKASKCCPNYACEWKYPWCRYKLF
Peptide Number
PHX001
Disulfide Bonds
Cys1-Cys4; Cys2-Cys5; Cys3-Cys6
N Terminal Sequence
H
C Terminal Sequence
OH
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