Echistatin α1 isoform
Echistatin was originally purified from the venom of the viper Echis carinatus. Echistatin is a cyclic RGD peptide that inhibits platelet aggregation by inhibiting the glycoprotein IIb/IIIa complex receptor. Echistatin is a potent disintegrin that antagonize αVβ3 integrin and has been described to inhibit cell proliferation, migration, invasion, and adhesion of αVβ3 expressing cells.
Product Specifications
Specifications
Antagonization of αVβ3 integrin. Inhibition of cell proliferation, migration, invasion, and adhesion of αVβ3 expressing cells.
Target
Integrins
Sequence
ECESGPCCRNCKFLKEGTICKRARGDDMDDYCNGKTCDCPRNPHKGPAT
Peptide Number
ECH001
Disulfide Bonds
Cys2-Cys11; Cys7-Cys32; Cys8-Cys37; Cys20-Cys39
N Terminal Sequence
H
C Terminal Sequence
OH
CAS Number
154303-05-6
Curated Selection
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