Apidaecin IB

Apidaecin IB is a proline-rich antimicrobial peptide (PrAMP) isolated from Apis mellifera hemolymph. Apidaecin IB mainly possesses activity against Gram-negative bacteria. It has been reported that Apidaecin IB is a non-lytic AMP which enters the cell and inhibits an intracellular target, the chaperone DnaK. Apidaecin IB is not toxic for humans and animals. It has been studied for treating systemic bacterial infections.