Nesbuvir
Product Specifications
UNSPSC Description
Nesbuvir is a nonnucleoside inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase.
Target Antigen
HCV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nesbuvir.html
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(C1=C(C2=CC=C(F)C=C2)OC3=CC(N(CCO)S(=O)(C)=O)=C(C4CC4)C=C13)NC
Molecular Weight
446.49
References & Citations
[1]Flint M, et al. Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034).
 Antimicrob Agents Chemother. 2009 Feb;53(2):401-11.|[2]Reich S, et al. Mechanisms of activity and inhibition of the hepatitis C virus RNA-dependent RNA polymerase.
 J Biol Chem. 2010 Apr 30;285(18):13685-93.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14775/Nesbuvir-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14775/Nesbuvir-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
691852-58-1
Available Sizes
Curated Selection
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