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Nesbuvir

Product Specifications

UNSPSC Description

Nesbuvir is a nonnucleoside inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase.

Target Antigen

HCV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nesbuvir.html

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O=C(C1=C(C2=CC=C(F)C=C2)OC3=CC(N(CCO)S(=O)(C)=O)=C(C4CC4)C=C13)NC

Molecular Weight

446.49

References & Citations

[1]Flint M, et al. Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034).
 Antimicrob Agents Chemother. 2009 Feb;53(2):401-11.|[2]Reich S, et al. Mechanisms of activity and inhibition of the hepatitis C virus RNA-dependent RNA polymerase.
 J Biol Chem. 2010 Apr 30;285(18):13685-93.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-14775/Nesbuvir-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-14775/Nesbuvir-SDS-MedChemExpress.pdf

Clinical Information

Phase 2

CAS Number

691852-58-1

Available Sizes

Curated Selection

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