Nesbuvir
Nesbuvir is a nonnucleoside inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase.
Product Specifications
CAS Number
[691852-58-1]
Product Name Alternative
HCV-796
UNSPSC
12352005
Target
HCV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nesbuvir.html
Concentration
10mM
Purity
99.21
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(C1=C(C2=CC=C(F)C=C2)OC3=CC(N(CCO)S(=O)(C)=O)=C(C4CC4)C=C13)NC
Molecular Formula
C22H23FN2O5S
Molecular Weight
446.49
References & Citations
[1]Flint M, et al. Selection and characterization of hepatitis C virus replicons dually resistant to the polymerase and protease inhibitors HCV-796 and boceprevir (SCH 503034) .
 Antimicrob Agents Chemother. 2009 Feb;53 (2) :401-11.|[2]Reich S, et al. Mechanisms of activity and inhibition of the hepatitis C virus RNA-dependent RNA polymerase.
 J Biol Chem. 2010 Apr 30;285 (18) :13685-93.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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