Neurolysin, Human (His)

Neurolysin protein is a multifunctional enzyme that hydrolyzes oligopeptides such as neurotensin, bradykinin, and dynorphin A. In addition to its role in oligopeptide metabolism, Neurolysin also modulates cannabinoid signaling pathways by promoting the degradation of vasopressin, an antagonist peptide of the cannabinoid receptor CNR1. Neurolysin Protein, Human (His) is the recombinant human-derived Neurolysin protein, expressed by E. coli , with N-His labeled tag. The total length of Neurolysin Protein, Human (His) is 667 a.a., with molecular weight of ~67 kDa.

SSYTVAGRNV LRWDLSPEQI KTRTEELIVQ TKQVYDAVGM LGIEEVTYEN CLQALADVEV KYIVERTMLD FPQHVSSDKE VRAASTEADK RLSRFDIEMS MRGDIFERIV HLQETCDLGK IKPEARRYLE KSIKMGKRNG LHLPEQVQNE IKSMKKRMSE LCIDFNKNLN EDDTFLVFSK AELGALPDDF IDSLEKTDDD KYKITLKYPH YFPVMKKCCI PETRRRMEMA FNTRCKEENT IILQQLLPLR TKVAKLLGYS THADFVLEMN TAKSTSRVTA FLDDLSQKLK PLGEAEREFI LNLKKKECKD RGFEYDGKIN AWDLYYYMTQ TEELKYSIDQ EFLKEYFPIE VVTEGLLNTY QELLGLSFEQ MTDAHVWNKS VTLYTVKDKA TGEVLGQFYL DLYPREGKYN HAACFGLQPG CLLPDGSRMM AVAALVVNFS QPVAGRPSLL RHDEVRTYFH EFGHVMHQIC AQTDFARFSG TNVETDFVEV PSQMLENWVW DVDSLRRLSK HYKDGSPIAD DLLEKLVASR LVNTGLLTLR QIVLSKVDQS LHTNTSLDAA SEYAKYCSEI LGVAATPGTN MPATFGHLAG GYDGQYYGYL WSEVFSMDMF YSCFKKEGIM NPEVGMKYRN LILKPGGSLD GMDMLHNFLK REPNQKAFLM SRGLHAP